tina huang data scientist

El Mirn has a significantly higher similarity to theVillabruna clusterthan Fournol 85 and Le Piage II, while the affinity to theVillabruna cluster in Le Piage II is not significantly higher than in Fournol 85 (Supplementary Data 2.D). C. Posth and H.Y. van de Loosdrecht, M. et al. Along with pushing for more accessibility, she also creates content around working in the tech industry, the challenges that come with it, and career advice. For consistency with the previously discussed nomenclature, we rename the EHG ancestryas the Sidelkino cluster(hereafter, Sidelkino cluster or ancestry). This process allowed us to assign an ancestral or derived haplogroup for covered branches, and to make corrections to calls in cases where, for instance, a more derived haplogroup was called because of residual ancient damage (C-to-T or G-to-A mismatches) in terminal read positions at diagnostic SNPs98 (Supplementary Data 1.A). In this episode we go through a couple really superb resumes that you should model yours after. F4-statistics also show that the approximately8.2ka Yuzhniy Oleniy Ostrov group from Karelia in western Russia formed by 19 genomes has comparable or lower affinity to Villabruna ancestry than all the other EHG groups (Supplementary Data 2.K). Despite this wide geographical range, it is not clear whether different groups associated with this culture originated from a common source population and how those groups were genetically related to each other. What is Kagi Chart in Data Visualization? 10 and 11). Tina Huang. Previously, she has interned at Goldman Sachs where she used Python and Scala to implement machine learning techniques for automated anomaly detection. Notably, and contrary to the report by Fu et al.4, another Gravettian-associated population from centralwestern Europe (Goyet in Belgium, n=6 individuals) is both geographically and genetically intermediate between the Vstonice and Fournol clusters. Were dedicated to providing you the best ofNews, with a focus on dependability andBusiness. 2023 in science - Wikipedia When expanded it provides a list of search options that will switch the search inputs to match the current selection. Our knowledge of the genetic relatedness and structure of ancient hunter-gatherers is however limited, owing to the scarceness and poor molecular preservation of human remains from that period3. Nature 534, 200205 (2016). Contrary to the proposal in Fu et al.4 but in agreement with Petr et al.17, we do not observe a substantial decrease of Neanderthal ancestry in most European hunter-gatherers through time (Supplementary Information, section6 and Supplementary Figs. Upper Palaeolithic genomes reveal deep roots of modern Eurasians. The mapped reads from the same individual and library set-up were merged and duplications were removed with DeDup. On the basis of f4-statistics, we find that individuals assigned to the Oberkassel cluster are closer to the Arene Candide 16 genome than any other Epigravettian-associated group from Italy (Supplementary Data 2.F). I can't believe we finally got to meet in person. Here is a sampling of five herbs that have demonstrated potential immune support benefits: 1. 6 and Supplementary Fig. Tina started her YouTube channel in 2020. Find contact's direct phone number, email address, work history, and more. 16, 224 (2015). This procedure allowed us to manually traverse the ISOGG Y-Haplogroup Tree, checking in a semi-automatic way which positions were covered. Wonderful course so far Tina. 15, 22792300 (2020). Commun. 3b). ADS All Rights Reserved. Tina Huang | Propel | Build Something Together Citing . This finding, in conjunction with the genetic affinity of the Villabruna cluster to ancient and present-day Near Eastern ancestries4,15,16 (Supplementary Information, section8, Supplementary Fig. 2, e190 (2006). Palaeogenomics of Upper Palaeolithic to Neolithic European hunter Its the complexity of product development, with all of its moving parts, that makes data immensely powerful. Pseudo-haploid genotypes were called on the targeted SNPs by randomly sampling a single allele at each position, resulting in individuals with 6,600 to 1.07 million SNPs covered on the 1.24-million-SNP panel (Extended Data Table 1 and Supplementary Data 1.A). Subsequently, I worked in bioinformatics for a year and then did my Master's in computer science (MCIT) at the University of Pennsylvania. use of cookies Extended Data Fig. Substantially contaminated libraries as well as marginally contaminated libraries of individually analysed genomes were filtered to maintain reads showing postmortem DNA damage (Methods and Supplementary Figs. Its mainly used in industries such as finance, insurance, healthcare, and insurance-related apps such as credit card applications, vehicle purchasing, etc. Individuals from northwestern Italy (Arene Candide 16), central Italy (Continenza) and Sicily fall on a phylogenetically more derived branch (group 2), which further diversified into a branch composed of Sicilian hunter-gatherers only (group 3). Hunter-gatherers carrying an admixed WHG/EHG genetic profile have been sequenced from various regions of northern and eastern Europe, raising the question of how these two types of ancestries formed and interacted with each other through time and space37,38,39,40. As she gains working experience with one of the FAANG companies, Tina continues to share interesting details about her career journey with the audience. a, Population structure among Epigravettian-associated populations revealed by a neighbour-joining tree based on pairwise f2 genetic distances. Ace the SQL part of any data science job interview and get hired. Bronk Ramsey, C. Bayesian analysis of radiocarbon dates. Google Scholar. Y.H. This figure shows (a) the distribution of and interaction between hunter-gatherer genetic ancestries and (b) a simplified schematic representation of major chrono-cultural subdivisions of the European Upper Palaeolithic (green blocks) followed by a grouped Mesolithic to Neolithic block (in gray). The authors declare no competing interests. Genomic data have shown that modern humans were present in western Eurasia1,2 at least 45ka. Rev. under exclusive license to Springer Nature Singapore Pte Ltd. 2022 R. Huang et al. The y axis shows the average of calibrated radiocarbon dates in thousands of years (kyr) (Supplementary Data 1.A). Is There a Role for Renal Denervation in the Treatment of Hypertension They, along with it, will be accessible to you indefinitely. ContamLD: estimation of ancient nuclear DNA contamination using breakdown of linkage disequilibrium. Financial support for ScienceDaily comes from advertisements and referral programs, where indicated. TV Actresses. Archaeological background, method descriptions and discussions additional to the main text, including sections 113, Figs. My name is Tina Huang and I'm a data scientist at a FAANG company. The genetic history of Ice Age Europe. The purified products were amplified in multiple 100l reactions using Herculase II Fusion DNA Polymerase (Agilent) following the manufacturers specifications with 0.3M of the IS5/IS6 primers. Powered by Symplectic part of Digital Science . Tina Huang - Test and Validation Engineer - LinkedIn It was awesome seeing the thought process behind each of the questions - it helps students immensely! The increasing level of admixture between distinct hunter-gatherer populations from around 8ka onwards indicates an intensified mobility of those forager groups. 5, 820825 (2021). 4 and Supplementary Data 3.C). R Programming in Data Science: High Variety Data SQL Server . NEWSLETTER: https://tinahuang.substack.com/ It's about learning, coding, and generally how to get your sh*t together c: I've been a FAANG data scientist f. DNA analysis of an early modern human from Tianyuan Cave, China. The Complete Power BI Practical Course 2020, The 7 Biggest Technology Trends Everyone Must Get Ready For in 2020. The long-lasting genetic continuity in Iberia is also reflected in the preservation until the Mesolithic of Y-chromosome haplogroup C, which was predominant in pre-LGM groups but rarely found after the LGM in other parts of Europe (Extended Data Figs. Echinacea, also known as Coneflower, is legendary for a reason: science has shown multiple species of Echinacea can provide potentially broad-reaching support for the innate and adaptive immune system. No need to do it alone our community of learners and instructors is there for you. After 2 washing steps using the manufacturers wash buffer, DNA was eluted in TET (10mM Tris, 1mM EDTA and 0.05% Tween) in two steps for a final volume of 100l. Pleistocene North African genomes link Near Eastern and sub-Saharan African human populations. First, we show that individuals associated with the Gravettian culture across Europe were not a biologically homogeneous population. In it, we laugh while discussing how to get started in data science and her learning/productivity tricks.Tina: Creates YouTube videos with millions of views on data science careers, learning to code, SQL, productivity, and study techniques. Is a data scientist at one of the world's largest tech companies (she keeps the firm anonymous so she can publish more freely). Previously worked at Goldman Sachs and the Ontario Institute for Cancer Research. Holds a Masters in Computer and Information Technology from the University of Pennsylvania and a bachelors in Pharmacology from the University of TorontoIn this episode, Tina details: Her guidance for preparing for a career in data science from scratch. Her five steps for consistently doing anything. Her strategies for learning effectively and efficiently. What the day-to-day is like for a data scientist at one of the worlds largest tech companies. The software languages she uses regularly. Her SQL course. How her science and computer science backgrounds help her as a data scientist today.Todays episode should be appealing to a broad audience, whether youre thinking of getting started in data science, are already an experienced data scientist, or youre more generally keen to pick up career and productivity tips from a light-hearted conversation.Thanks to Serg Mass, Brindha Ganesan and Ken Jee for providing questions for Tina in Ken's case, a very silly question indeed.The SuperDataScience show's available on all major podcasting platforms, YouTube, and at SuperDataScience.com. EY. Ringbauer, H., Novembre, J. 15, 193223 (2005). You have to deal with large datasets; however, you have to do your work in a way that makes sense to your team. In this admixture graph, the lineage related to Zlat k splits more basally than the Bacho Kiro IUP group, who contributes to Tianyuan, UstIshim and Goyet Q116-1 (indicated with red lines), but not to the Sunghir group. The Roger Rabbit's Trousers (1990 film) Credits | JH Movie Collection 9 Graphical summary depicting the main genetic transformations in post-40 ka hunter-gatherers from Europe. This course will help you build a deliberate strategy when participating in a data scientist job interview involving SQL. My name is Tina and I'm a data scientist and YouTuber. Single-stranded DNA libraries were built from 30l of DNA extract in the absence of uracil DNA glycosylase (ss_nonUDG) followed by double indexing, using an automated version of the protocols described in61 on the liquid handling system mentioned before. Olalde, I. et al. Purchasing this course makes it your own. Hi, my name is Tina and I'm a data scientist at a FAANG company. The triangles show the average calibrated dates of the tested groups and the dots show the estimated admixture dates with the software DATES105 using Oberkassel (red dots) or Villabruna (blue dots) clusters as one source and ANE-related individuals as the other source population. I hold a Bachelor's degree at the University of Toronto where I studied pharmacology. Proc. Biol. Nat. Sci. 6 West Eurasian PCA showing the genetic positioning of post-LGM hunter-gatherers. A genome sequence from a modern human skull over 45,000 years old from Zlat k in Czechia. Hutong Cat | China and Russia's invasion of Ukraine: A year later Tina Huang - Data Scientist - Children's Hospital Los Angeles (CHLA Shes currently at Microsoft. eLife 11, e77625 (2022). Consultant - October 2015 to June 2016. 211 and Supplementary Table 1). View Tina Huang's profile on LinkedIn, the world's largest professional community. In each of the past 200 years they have only seen four new entrants into their top 200 list. Further information on research design is available in theNature Portfolio Reporting Summary linked to this article. Some of those early groups from more than 40ka further admixed with Neanderthals, as shown by signals of recent introgression in individuals from Bacho Kiro in Bulgariaassociated with an Initial Upper Palaeolithic (IUP) archaeological cultureand from Petera cu Oase in Romania2,6. Reviews. This is further validated by f4-statistics of the form f4(Mbuti, Arene Candide 16; Goyet Q-2, Magdalenian-associated individuals), which is significantly positive only for El Mirn, whereas all other tested individuals and Goyet Q-2 are symmetrically related with respect to Arene Candide 16 (Supplementary Fig. K.N., V.V.-M., R.R., T. Ferraz, R.T., D.G.D., M.L., A. Modi, S. Vai, T. Saupe, C.L.S., G. Catalano, L. Pagani, D.C. and E.A. Schubert, M., Lindgreen, S. & Orlando, L. AdapterRemoval v2: rapid adapter trimming, identification, and read merging. & Dolukhanov, P.) 122145 (Avebury, 1993). Adv. hellotinah The mitochondrial capture sequencing reads were cleaned by AdapterRemoval 2.2.0 to remove the adapters and reads with lengths below 30bp. I am Tina Huang, PhD, a data scientist, and the director of the Data Science Learning Center at the University of Arizona. Commun. The LGM could thus have created a corridor south of the Alps for east-to-west human movements that genetically connected hunter-gatherer populations from the Balkans to Iberia, possibly also via dispersals along existing lower-sea-level coasts32. It is not intended to provide medical or other professional advice. She then served as a postdoctoral associate at the National Institute of Standards and Technology. Int. Second, the ancestry of individuals associated with the Epigravettian culture (Villabruna cluster), which was found to genetically connect European and Near Eastern hunter-gatherers, reached southern Europe well before the transition between the Early and Late Epigravettian4,15 and possibly as early as the GravettianEpigravettian transition. Peresani, M. et al. 272273, 354361 (2012). Advanced Science: Vol 10, No 7 - onlinelibrary.wiley.com 5 and Supplementary Information, section9). Nat. Nucleic Acids Res. Shes the founder of Coding Black Females, a nonprofit with the aim to provide opportunities for Black female developers to develop themselves, meet familiar faces, network, receive support, and build relationships through having regular meetups., Check out the Coding Black Females website. In the MDS plot (Fig. Reducing microbial and human contamination in DNA extractions from ancient bones and teeth. Tina Huang Profile | University of Auckland All enrolled students have access to course exams no matter how many lessons they have watched in a course. Emergence of human-adapted Salmonella enterica is linked to the Neolithization process. Harris, K. & Nielsen, R. The genetic cost of Neanderthal introgression. The deduplicated bam files were filtered using PMDtools 0.6068 with a threshold of 3, to reduce potential modern DNA contamination based on postmortem DNA deamination. Individuals at this site might mark one of the last occurrences of such high levels of hunter-gatherer-related ancestries, just centuries before the emerging European Bronze Age. Article Nature 582, 384388 (2020). Nat. "It is possible that the migration of early farmers into Europe triggered the retreat of hunter-gatherer populations to the northern edge of Europe. In this study, we analyse 356 ancient hunter-gatherer genomes including new genomic data of 116 individuals dated to 355ka alongside a novel contamination-estimation method based on runs of homozygosity. and T. Saupe received support from the European Union through the European Regional Development Fund (project no. This might also explain the genetic uniformity of the Oberkassel cluster across large parts of western Eurasia but genomic data from between 15 and 14ka is needed to understand the exact dynamics of this turnover. Corporate Financial Managementspring term (BS 2508) Second year of undergraduate. This channel is about data science, learning, and productivity. Views expressed here do not necessarily reflect those of ScienceDaily, its staff, its contributors, or its partners. The pathway program not only helps students to strengthen their English, but more importantly, it helps students to understand and adapt to the expections of university.".

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